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Diazepam is very lipid-soluble, and is greatly distributed all through the human body after administration. It simply crosses both of those the blood–brain barrier and the placenta, and it is excreted into breast milk.
Alcohol in combination with diazepam may bring about a synergistic improvement of the hypotensive Qualities of benzodiazepines and Alcoholic beverages.[ninety two]
Libervant is really a buccally, or within the cheek, administered movie formulation of diazepam, a benzodiazepine intended for that acute treatment of intermittent, stereotypic episodes of Repeated seizure exercise (
The mixture of both of these CNS depressants can cause Unintended effects including an unusually very low heartbeat and respiratory challenges.
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